HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 2-mercapto-, methyl ester → 52947-34-9
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Ethyl 2-chloroethanecarboximidate hydrochloride | HCID 12470659 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 52947-34-9 | HCID 3040798 | — |
Reaction Steps
A solution of 23 g (1 mol) of sodium in 1 l of anhydrous methanol is mixed with 84 g (0.5 mol) of methyl thiosalicylate while stirring. This is then mixed with 79 g (0.5 mol) of ethyl chloro-acetimidate hydrochloride and heated under reflux for 10 hours. The sodium chloride precipitate is filtered off and the desired product isolated by evaporation (yield: 73 g, m.p. 201° C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04056526 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-32a4ae0098f5414abecf0749eef35871 |
| Source note | uspto-grants-1977_11 |