HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 9-carboxy-11H-pyrrolo[2,1-b][3]benzazepin-11-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | HCID 20310586 | HCID 20310586 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Water | HCID 962 | — |
| Product | 9-carboxy-11H-pyrrolo[2,1-b][3]benzazepin-11-one | HCID 13154199 | — |
Reaction Steps
To 9-carbamoyl-11H-pyrrolo[2,1-b] [3]-benzazepin-11-one (27 g., 0.112 moles) in 300 ml. of 50% sulfuric acid maintained at 50° C. is added slowly 25 g. of sodium nitrite in 75 ml. of water. At the end of the addition, the solid is filtered, washed with water and air-dried to yield 9-carboxy-11H-pyrrolo[2,1-b] [3]benzazepin-11-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04056536 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-e64f585b0fda4b16899fd10e750d30b4 |
| Source note | uspto-grants-1977_11 |