HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diboron → 4H-1,3-Benzodioxin-2-methanamine, 6-chloro-N-methyl-4-phenyl-, hydrochloride, cis-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diboron | HCID 6328200 | — |
| Reactant | HCID 22799981 | HCID 22799981 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4H-1,3-Benzodioxin-2-methanamine, 6-chloro-N-methyl-4-phenyl-, hydrochloride, cis- | HCID 3049700 | — |
Reaction Steps
To a stirred solution, under nitrogen, of 8.0 g (26.4 mmoles) of cis-6-chloro-N-methyl-4-phenyl-1,3-benzodioxan-2-carboxamide was added dropwise, at room temperature, 150 ml (150 mmoles) of diborane (1M as BH3) in THF solution. After addition was complete, the solution was stirred and refluxed for 21 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04056540 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-a9f83d31989a46ec93b080c4b94f3b43 |
| Source note | uspto-grants-1977_11 |