HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 1,1-Diphenyl-3-bromopropan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 3-Bromo-1,1-diphenylacetone | HCID 2794635 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 1,1-Diphenyl-3-bromopropan-2-ol | HCID 12549067 | 86% |
Reaction Steps
Sodium borohydride (1 52g) in sodium hydroxide solution (15 ml 0.02M) was added to 1,1-diphenyl-3-bromo-propan-2-one (12g) in methanol (50 ml) and the solution was stirred for one hour. Isolation through ether in the usual manner afforded 1,1-diphenyl-3-bromo-propan-2-ol (10.4g 86%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04056630 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-3a8e4019bdc9471882738e2ad8adf007 |
| Source note | uspto-grants-1977_11 |