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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1438863Generated: November 2, 2026

Acetic Acid → 2-(4-Hydroxyphenyl)indole

https://huagongshe.com/reaction/1438863

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantEthanolHCID 702—
ReactantPhenylhydrazineHCID 7516—
Product2-(4-Hydroxyphenyl)indoleHCID 11287260—

Reaction Steps

A mixture of 40.8 g (0.3 mol) of 4-hydroxy-acetophenone, 33 ml (0.3 mol) of phenylhydrazine, 100 ml of ethanol and 1.5 ml of acetic acid was refluxed under nitrogen for 10 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04057530
Source datasetuspto-grants-1977_11
ORD IDord-3dce05dd5b0845b9b1e3b409d59560a8
Source noteuspto-grants-1977_11