Trimethylpyruvic acid → HCID 178441961, compound

HRID 1438910Notes

Reaction equation

HRID 1438910 reaction equation
[NH2:1][NH:2][C:3]([NH:5][NH2:6])=[S:4].[CH3:7][C:8]([CH3:15])([CH3:14])[C:9](=O)[C:10](O)=[O:11]>O>[C:8]([C:9]1[C:10](=[O:11])[N:2]([NH2:1])[C:3]([SH:4])=[N:5][N:6]=1)([CH3:15])([CH3:14])[CH3:7]

Participants

4

Reactant 2

HCID 13150Trimethylpyruvic acidHCID 2724189Thiocarbohydrazide

Product 1

HCID 178441961HCID 178441961, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Analogously to instructions given by A. Dornow and others (Chem. Brichte 97 (1964), page 2173-2178), 53 g (0.5 mole) of thiocarbohydrazide are dissolved in 500 ml of boiling water and 65 g (0.5 mole) of trimethylpyruvic acid are added slowly. A colorless precipitate is deposited, which is filtered off, washed with water and dried in vacuo at 50° C. 6-tert.-butyl-3-mercapto-4-amino-1,2,4-triazin-5(4H)-one is obtained from this reaction in almost quantitative yield.

Workup

  1. filtrationwhich is filtered off
  2. washwashed with water
  3. customdried in vacuo at 50° C

Sources & evidence

ORD record
ord-b5cad4740db24b60b77819cacdf24e91
Source dataset
uspto-grants-1977_11
Patent number
US04057583

Reaction notes

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