4-Chlorobenzoyl chloride → HCID 54329928, compound

HRID 1438930Notes

Reaction equation

HRID 1438930 reaction equation
[CH3:1][O:2][C:3]([CH:5]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([O:14]C)[CH:12]=2)[CH2:7][CH2:6]1)=[O:4].[Cl:16][C:17]1[CH:25]=[CH:24][C:20]([C:21](Cl)=[O:22])=[CH:19][CH:18]=1>>[CH3:1][O:2][C:3]([CH:5]1[C:13]2[C:8](=[CH:9][C:10]([C:21](=[O:22])[C:20]3[CH:24]=[CH:25][C:17]([Cl:16])=[CH:18][CH:19]=3)=[C:11]([OH:14])[CH:12]=2)[CH2:7][CH2:6]1)=[O:4]

Participants

3

Reactant 2

HCID 85014-Chlorobenzoyl chlorideHCID 14843791Methyl 2,3-dihydro-6-methoxy-1H-indene-1-carboxylate

Product 1

HCID 54329928HCID 54329928, compound

Procedure

Analogously to the process described in Example 5, 19 g of 6-methoxy-indane-1-carboxylic acid methyl ester and 48 g of p-chlorobenzoyl chloride give 5-(p-chlorobenzoyl)-6-hydroxy-indane-1-carboxylic acid methyl ester of melting point 96°-98° C (from ether-petroleum ether.

Sources & evidence

ORD record
ord-9ca36aad581e4726a76f13c0adcb1e6a
Source dataset
uspto-grants-1977_11
Patent number
US04057573

Reaction notes

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