Methanol → HCID 54520772, compound

HRID 1438932Notes

Reaction equation

HRID 1438932 reaction equation
[OH-].[Na+].[C:3]1([C:8]([C:10]2[CH:11]=[C:12]3[C:16](=[CH:17][C:18]=2[OH:19])[CH:15]([C:20]([OH:22])=[O:21])[CH2:14][CH2:13]3)=[O:9])[S:7][CH:6]=[CH:5][CH:4]=1.[CH3:23]O>>[CH3:23][O:21][C:20]([CH:15]1[C:16]2[C:12](=[CH:11][C:10]([C:8](=[O:9])[C:3]3[S:7][CH:6]=[CH:5][CH:4]=3)=[C:18]([OH:19])[CH:17]=2)[CH2:13][CH2:14]1)=[O:22]

Participants

4

Reactant 3

HCID 887MethanolHCID 14798Sodium HydroxideHCID 23457894HCID 23457894, compound

Product 1

HCID 54520772HCID 54520772, compound

Procedure

Analogously to the description in Example 2, 4.0 g of 5-thenoyl-6-hydroxy-indane-1-carboxylic acid methyl ester and 20 ml of 2N sodium hydroxide solution in 50 ml of methanol give 5-thenoyl-6-hydroxy-indane-1-carboxylic acid of melting point 183°-184° C (from ethyl acetate/petroleum ether).

Sources & evidence

ORD record
ord-fdba008bd99a48d888b720aad86dec42
Source dataset
uspto-grants-1977_11
Patent number
US04057573

Reaction notes

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