HCID 20501879, compound → HCID 178449187, compound

HRID 1438971Notes

Reaction equation

HRID 1438971 reaction equation
[C:1]([NH:5][C:6]([NH:8][C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)=S)([CH3:4])([CH3:3])[CH3:2].[N:15]#[C:16][NH2:17].[Pb]>C(O)C>[C:1]([NH:5][C:6]([NH:8][C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)=[N:17][C:16]#[N:15])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 20501879HCID 20501879, compoundHCID 22262466CH2N2Pb

Product 1

HCID 178449187HCID 178449187, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

N-tert-butyl-N'-3-pyridylthiourea (2.1 g) and lead cyanamide (3.7 g) were refluxed in ethanol (20 ml) for 18 hours. The mixture was filtered, and the filtrate was evaporated in vacuo to afford the crude product. Recrystallization from aqueous acetone gave the desired compound. Melting point 205.0°-206.5° C.

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate was evaporated in vacuo
  3. customto afford the crude product
  4. customRecrystallization from aqueous acetone

Sources & evidence

ORD record
ord-6d02832fadea4d0cba8619f718a01da0
Source dataset
uspto-grants-1977_11
Patent number
US04057636

Reaction notes

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