HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → Methyl 4-(5-chlorobenzothiazol-2-yl)allophanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 5-Chloro-2-benzothiazolamine | HCID 30120 | — |
| Reactant | Methyl isocyanatoformate | HCID 4156749 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Methyl 4-(5-chlorobenzothiazol-2-yl)allophanate | HCID 21399908 | 85% |
Reaction Steps
One part by weight of methoxycarbonyl isocyanate was added gradually with stirring to a solution of 2 parts by weight of 2-amino-5-chlorobenzothiazole in 100 parts by weight of methylene chloride and 50 parts by weight of ethyl ether. After stirring the reaction mixture at room temperature overnight, a product was isolated by filtration giving an 85% yield of methyl 4-(5-chlorobenzothiazol-2-yl)allophanate having a melting point of 395°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04057638 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-89999c4997814cb6b13f2981cbb1ca58 |
| Source note | uspto-grants-1977_11 |