HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylanthranilic acid → 9-Methyl-5,6,7,8-tetrahydrocarbazole-1-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylanthranilic acid | HCID 67069 | — |
| Reactant | 2-Bromocyclohexanone | HCID 11789758 | — |
| Product | 9-Methyl-5,6,7,8-tetrahydrocarbazole-1-carboxylic acid | HCID 21399959 | 15% |
Reaction Steps
Under the conditions of Example 59, 2-bromocyclohexanone is reacted with the methyl ester of N-methylanthranilic acid. After recrystallization from methanol, the methyl ester of 9-methyl-5,6,7,8-tetrahydrocarbazole-1-carboxylic acid is obtained in a 15% yield, m.p. 56° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04057640 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-931aa3ebb34646b3a5ae4a4ff6fd3ba4 |
| Source note | uspto-grants-1977_11 |