HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Methylthiobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Methylthiobenzoic acid | HCID 178425911 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 4-Methylthiobenzoyl chloride | HCID 15555005 | — |
Reaction Steps
4-Methylthiobenzoic acid, 16.8 g (0.1 mole) is refluxed for 30 minutes in 50 ml of thionyl chloride (SOCl2) and 1 drop of dimethylformamide (DMF). The thionyl chloride is removed under vacuum and azeotroped with 50 ml of benzene to give 4-methylthiobenzoyl chloride as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04057642 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-b7ef452265ec4dd79cc1e3a73c20dcdb |
| Source note | uspto-grants-1977_11 |