HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid → 3-(2',4'-Difluoro-4-biphenylyl)butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid | HCID 21322583 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-(2',4'-Difluoro-4-biphenylyl)butyric acid | HCID 21322540 | — |
Reaction Steps
A solution of 3.18 g. of 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid in 30 ml. of acetic acid is hydrogenated, at 20° and under normal pressure, on 0.2 g. of 10% Pd/C in the presence of 0.01 ml. of HClO4. The mixture is filtered and the filtrate is diluted with water to give 3-(2',4'-difluoro-4-biphenylyl)butyric acid, m.p. 109°-110°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04057647 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-3f4d1ec06cd44f16bf9462583414e182 |
| Source note | uspto-grants-1977_11 |