HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(2',4'-Difluoro-4-biphenylyl)butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(2',4'-Difluoro-4-biphenylyl)butyric acid ethyl ester | HCID 54340187 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-(2',4'-Difluoro-4-biphenylyl)butyric acid | HCID 21322540 | — |
Reaction Steps
3.04 g. of 3-(2',4'-difluoro-4-biphenylyl)butyric acid ethyl ester in a mixture of 25 ml. of acetic acid and 25 ml of 25% hydrochloric acid are heated under reflux for 90 minutes. The customary work up gives 3-(2',4'-difluoro-4-biphenylyl)butyric acid, m.p. 109°-110°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04057647 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-cf6f473ce3da40108c38e5c479c6eb0a |
| Source note | uspto-grants-1977_11 |