2-Benzoylbenzoic Acid → HCID 21398385, compound

Participants

Reaction Steps

22.6 Parts of o-benzoyl-benzoic acid are dissolved in 100 ml of chlorobenzene. 7.4 Parts of N-methylethylenediamine are added within 10 minutes. The temperature is then raised within 1 - 2 hours to such an extent that some chlorobenzene is continuously distilled off with the reaction water until the boiling point of the pure chlorobenzene (130°-132°) is attained. 80-90% of the theoretical amount of reaction water can be removed from the distillate. The remainder of the chlorobenzene is distilled off from the reaction mass in vacuo and the viscous oil which remains is crystallised by the addition of about 10 parts of ethyl acetate. The 1-methyl-9b-phenyl-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one so obtained of the formula ##STR10## is filtered off and recrystallised from a mixture of 30 parts of ethyl acetate and 30 parts of petroleum ether (B.P. 30°-60° ). M.P. 120°-122°.

Provenance & Evidence