Putrescine → HCID 12204569, compound

Participants

Reaction Steps

22.6 Parts of o-benzoyl-benzoic acid and 10.1 parts of 1,4-butanediamine in 100 parts by volume of o-dichlorobenzene are heated within 2 hours to 179° whereby reaction water and a little dichlorobenzene azeotropically distill off. The solvent is then distilled off in vacuo whereupon an oil remains which spontaneously crystallises after some time. On recrystallising from benzene, the pure 11b-phenyl-1,2,3,4,5,11b-hexahydro-7H-[1,3]-diazepino[2,1-a]isoindol-7-one is obtained of the formula ##STR21## It melts at 180°-181°. On using o-(p'-chlorobenzoyl)-benzoic acid, 11b-(p-chlorophenyl)-1,2,3,4,5,11b-hexahydro-7H-[1,3]diazepino[2,1-a]isoindol-7-one is obtained in the same manner. It melts at 134°-135°.

Provenance & Evidence