HCID 22800117, compound → HCID 54259699, compound

HRID 1439188Notes

Reaction equation

HRID 1439188 reaction equation
[OH:1][C@H:2]1[CH2:19][CH2:18][C@@:17]2([CH2:20][OH:21])[C:4]([CH:5]=[CH:6][C:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C:8]=3[CH2:9][CH2:10][C@@H:11]2[OH:22])=[CH:3]1>CCOCC>[OH:22][C@H:11]1[CH2:10][CH2:9][C:8]2=[C:7]3[C@H:16]([CH2:15][CH2:14][C@:12]12[CH3:13])[C@:17]1([CH2:20][OH:21])[C:4](=[CH:3][C:2](=[O:1])[CH2:19][CH2:18]1)[CH:5]=[CH:6]3

Participants

3

Reactant 1

HCID 22800117HCID 22800117, compound

Product 1

HCID 54259699HCID 54259699, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of 20 mg. of 3β,17β,19-trihydroxyandrosta-4,6,8(14)-triene, 20 mg. of dichlorodicyanoquinone and 2.0 ml. of ether was shaken under nitrogen for 20 minutes. Subsequent filtration afforded the compound 17β,19-dihydroxyandrosta-4,6,8-(14)-trien-3-one, λ max 344 mμ.

Workup

  1. additionA mixture of 20 mg
  2. filtrationSubsequent filtration

Sources & evidence

ORD record
ord-ca97c83a2e934a3497535c66552a2f4b
Source dataset
uspto-grants-1977_11
Patent number
US04058539

Reaction notes

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