Acetic Anhydride → HCID 22800116, compound

HRID 1439191Notes

Reaction equation

HRID 1439191 reaction equation
[OH:1][C@H:2]1[CH2:19][CH2:18][C@@:17]2([CH2:20][OH:21])[C:4]([CH:5]=[CH:6][C:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C:8]=3[CH2:9][CH2:10][C@@H:11]2[OH:22])=[CH:3]1.C(O[C:27](=[O:29])[CH3:28])(=O)C>N1C=CC=CC=1>[C:2]([O:1][C@H:2]1[CH2:19][CH2:18][C@@:17]2([CH2:20][O:21][C:20](=[O:21])[CH3:17])[C:4]([CH:5]=[CH:6][C:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C:8]=3[CH2:9][CH2:10][C@@H:11]2[O:22][C:27](=[O:29])[CH3:28])=[CH:3]1)(=[O:1])[CH3:3]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 22800117HCID 22800117, compound

Product 1

HCID 22800116HCID 22800116, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A mixture of 500 mg of 3β,17β,19-trihydroxyandrosta-4,6,8(14)-triene, 1.0 ml of pyridine and 0.5 ml of acetic anhydride was left to stand at room temperature for 16 hours in an atmosphere of nitrogen. Dilution with water, followed by extraction with ether and concentration at reduced pressure gave 3β,17β,19-triacetoxyandrosta-4,6,8(14)-triene as a white crystalline product.

Workup

  1. waitwas left
  2. extractionDilution with water, followed by extraction with ether and concentration at reduced pressure

Sources & evidence

ORD record
ord-9708f583e19e47a28b2e4f27cc0e9bb8
Source dataset
uspto-grants-1977_11
Patent number
US04058539

Reaction notes

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