Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | Hydrofluoric Acid | HCID 14917 | — |
| Reactant | HCID 20437441 | HCID 20437441 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 53720207 | HCID 53720207 | 71.4% |
Reaction Steps
To a mixture of 3.53g of anhydrous hydrogen fluoride in 150 ml of toluene cooled to -50° C. was added dropwise 10.05g of methyl isocyanate. After stirring for 1.5 hr. at 0° C, 30.0g of approximately 85 percent pure 1-chloro-2-cyano-2-propanesulfenyl chloride was added followed by dropwise addition of 17.8g of triethylamine. During the addition of base the temperature was maintained between 0° C and 10° C. After stirring for an additional 1 hr., the precipitated salt was removed by filtration and the filtrate was concentrated to yield 26.5g of a light yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04058549 |
|---|
| Source dataset | uspto-grants-1977_11 |
|---|
| ORD ID | ord-2a9766eab177434e87e53d79afe3b8a6 |
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| Source note | uspto-grants-1977_11 |
|---|
