Aniline → alpha-Hydroxyacetophenone

Participants

Reaction Steps

In a third method the 1,2-diphenylquinolones (IV, m = 0) are prepared by acylation of an appropriate aniline with an appropriate benzoyl chloride, chlorination of the resulting benzanilide, reaction of the benzimidoyl chloride so obtained with an appropriate 2-hydroxyacetophenone and rearrangement of the resulting 2-acetylphenyl N-phenylbenzimidate. The sequence of reactions is illustrated by the following equations: ##STR9##

Provenance & Evidence