HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1439282Generated: November 1, 2026
Glycerol → 2,3-Dihydroxypropyl 4-(n-hexadecylamino)benzoate
https://huagongshe.com/reaction/1439282
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Glycerol | HCID 753 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | HCID 20437362 | HCID 20437362 | — |
| Product | 2,3-Dihydroxypropyl 4-(n-hexadecylamino)benzoate | HCID 13019380 | — |
Reaction Steps
A mixture of 2.25 g of methyl 4-(n-hexadecylamino)benzoate, 280 mg of glycerol, and 1.37 g of p-toluenesulfonic acid is heated at 180° C for 18 hours and then is partitioned between ether and 3% aqueous carbonate solution. The ether layer is separated, dried, and evaporated to yield 2,3-dihydroxypropyl 4-(n-hexadecylamino)benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04058550 |
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| Source dataset | uspto-grants-1977_11 |
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| ORD ID | ord-65d2f090a0ed43cc9a7c1e5153f01d23 |
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| Source note | uspto-grants-1977_11 |
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