HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1439283Generated: October 31, 2026
Glycerol → 2,3-Dihydroxypropyl 4-(n-hexadecylamino)benzoate
https://huagongshe.com/reaction/1439283
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Glycerol | HCID 753 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-(Hexadecylamino)benzoic acid | HCID 47263 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2,3-Dihydroxypropyl 4-(n-hexadecylamino)benzoate | HCID 13019380 | — |
Reaction Steps
A mixture of 722 mg of 4-(n-hexadecylamino)benzoic acid, 736 mg of glycerol, and 412 mg of p-toluene sulfonic acid is heated for 4 hours at 120° C, allowed to cool, and then is treated with ether and 2% aqueous sodium carbonate solution. Filtration affords a white solid which is recrystallized from chloroform to yield 2,3-dihydroxypropyl 4-(n-hexadecylamino)benzoate, mp 112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04058550 |
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| Source dataset | uspto-grants-1977_11 |
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| ORD ID | ord-6ac1ecacad67487f9a4989af1d2e6376 |
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| Source note | uspto-grants-1977_11 |
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