Dimethylamine → HCID 21396822, compound

Participants

Reaction Steps

In the manner of Example II B, 8.4 g of phenyl (3-ethoxy-4-ethoxycarbonyl-5-isothiazolyl)carbamate in 20 ml of dimethylformamide were treated with 2.3 g of dimethylamine. The solid from the reaction mixture was recrystallized from ethanol to yield 1.9 g of 1,1-dimethyl-3-(3-ethoxy-4-ethoxycarbonyl-5-isothiazolyl)urea, mp 164°-165°. The ir and nmr spectra were consistent with the assigned structure.

Provenance & Evidence