HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Chloro-2-fluoroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4'-Chloro-2'-fluoroacetanilide | HCID 853174 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Chloro-2-fluoroaniline | HCID 93898 | — |
Reaction Steps
A mixture of 119 parts of 4'-chloro-2'-fluoroacetanilide in 475 parts of ethanol and 200 parts of 37% hydrochloric acid was refluxed for 17 hours and the solvent removed under a reduced pressure of 300 mm. Hg to yield the moist, solid hydrochloride salt of 4-chloro-2-fluoroaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04059434 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-e3794c371fa04ef58709da2a074859a8 |
| Source note | uspto-grants-1977_11 |