m-Chloroperbenzoic acid → HCID 86735206, compound

Participants

Reaction Steps

To a cold solution (5° - 15° C) of 1,7,8,12b-tetrahydrobenzo[1,2]-cyclohepta[3,4,5-de]isoquinoline (2.7 g) in chloroform (30 ml), a solution of m-chloroperbenzoic acid (2.3 g) in 20 ml of chloroform is added dropwise. The reaction mixture is allowed to stand at room temperature (i.e., 20° - 25° C) for 30 minutes. The reaction mixture is then washed with 15% ammonium hydroxide and water. The reaction mixture is dried (MgSO4) and concentrated to yield an oily residue. The oily residue is crystallized from benzene/hexane to give the title compound, mp 156° - 158° C.

Provenance & Evidence