4-Nitrobenzoyl chloride → HCID 21397620, compound

HRID 1439426Notes

Reaction equation

HRID 1439426 reaction equation
Cl.[N+](C1C=CC(C([NH:11][CH2:12][CH:13]([OH:26])[CH2:14][N:15]([CH:23]([CH3:25])[CH3:24])[CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=O)=CC=1)([O-])=O.[N+](C1C=CC(C(Cl)=O)=CC=1)([O-])=O>>[NH2:11][CH2:12][CH:13]([OH:26])[CH2:14][N:15]([CH:23]([CH3:24])[CH3:25])[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 85024-Nitrobenzoyl chlorideHCID 21397630HCID 21397630, compound

Product 1

HCID 21397620HCID 21397620, compoundYield 71%

Procedure

1-(4-nitro benzamido)-3-(N-benzyl isopropylamino)-2-propanol hydrochloride, M. Pt. 163°-164° C, starting from 7.2 g (0.039 mole) of 4-nitro benzoyl chloride and 8.65 g (0.039 mole) of 1-amino-3-(N-benzyl isopropylamino)-2-propanol (yield 71%).

Sources & evidence

ORD record
ord-fe97faf4470d4cf7b5b4c9a156c5656f
Source dataset
uspto-grants-1977_11
Patent number
US04059621

Reaction notes

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