HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Benzodioxole-5-carbonyl chloride → 1-Amino-3-[(1,1-dimethylethyl)(phenylmethyl)amino]propan-2-OL
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Benzodioxole-5-carbonyl chloride | HCID 2734749 | — |
| Reactant | 1-(3,4-methylenedioxy benzamido)-3-(N-benzyl tert-butylamino)-2-propanol hydrochloride | HCID 131710951 | — |
| Product | 1-Amino-3-[(1,1-dimethylethyl)(phenylmethyl)amino]propan-2-OL | HCID 3016524 | 80% |
Reaction Steps
1-(3,4-methylenedioxy benzamido)-3-(N-benzyl tert-butylamino)-2- propanol hydrochloride, starting from 6.3 g (0.034 mole) of 3,4-methylenedioxy benzoyl chloride and 8 g (0.034 mole) of 1-amino-3-(N-benzyl tert-butylamino)-2- propanol (yield 80 %).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04059621 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-a4eacd56c26c4074825c045d053fe73e |
| Source note | uspto-grants-1977_11 |