Benzene → HCID 86734477, compound

Participants

Reaction Steps

Approximately 5.9 grams (0.04M) of 1-oximino-2-chlorocyclohexane is dissolved in 90 ml. of benzene and the solution is cooled to 10° C. About 8.1 gm. (0.04M) bromoacetyl bromide, diluted with 10 ml. of benzene, and 4.9 grams (6.7 ml.) of triethylamine are added dropwise simultaneously to the solution. Stirring is continued for 30 minutes and the mixture is allowed to come to room temperature. The mixture is then washed twice with water, twice with a mild NaHCO3 solution, and again with water. The mixture is then dried over MgSO4, and the solvent is evaporated to give the product 2-chlorocyclohexanone oxime bromoacetate.

Provenance & Evidence