Benzyl Alcohol → N,N-Dimethylbenzylamine

HRID 1439444Notes

Reaction equation

[CH2:1](O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:9][N:10](C)[CH3:11].[C]=O>>[CH2:1]([N:10]([CH3:11])[CH3:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 3

HCID 244Benzyl Alcohol

HCID 1146Trimethylamine

HCID 178418416HCID 178418416, compound

Product 1

HCID 7681N,N-Dimethylbenzylamine

Conditions

Temperature: 200 °C

Procedure

To a glass-lined, stainless steel microreactor were charged 2 ml of benzyl alcohol, 1 ml of trimethylamine, and carbon monoxide (900 psi). The reactor was shaken 5 hours at 200° C. A large yield of benzyldimethylamine was obtained.

Sources & evidence

ORD record: ord-8bdcdb87d7444ba193aebb0b1a970746
Source dataset: uspto-grants-1977_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04059640

Reaction notes

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