Hexafluoroacetone → 2,2-Bis(trifluoromethyl)-4-hydroxymethyl-1,3-dioxolane

HRID 1439522Notes

Reaction equation

[F:1][C:2]([F:10])([F:9])[C:3]([C:5]([F:8])([F:7])[F:6])=[O:4].[OH:11][CH2:12][CH:13]1[CH2:17]OC(=O)[O:14]1>>[F:1][C:2]([F:10])([F:9])[C:3]1([C:5]([F:8])([F:7])[F:6])[O:14][CH:13]([CH2:12][OH:11])[CH2:17][O:4]1

Participants

Reactant 2

HCID 12695Hexafluoroacetone

HCID 97944Glycerol carbonate

Product 1

HCID 219971032,2-Bis(trifluoromethyl)-4-hydroxymethyl-1,3-dioxolaneYield 66%

Procedure

8.5 grams of this hydroxyethyl hemiketal of hexafluoroacetone is then reacted with 3 grams of glycerol carbonate at 115°-141° C. for 103 hours. The yield is 66% 2,2-bis(trifluoromethyl)-4-hydroxymethyl-1,3-dioxolane.

Sources & evidence

ORD record: ord-591059ed401c48fd9a67644ca48ed125
Source dataset: uspto-grants-1977_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04060532

Reaction notes

Loading…