Thionyl Chloride → HCID 20338242, compound

HRID 1439613Notes

Reaction equation

HRID 1439613 reaction equation
[CH2:1]([N:8]([CH2:18][CH2:19]O)[C:9]1[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=1[C:11]([NH2:13])=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O=S(Cl)[Cl:23]>>[ClH:23].[CH2:1]([N:8]([CH2:18][CH2:19][Cl:23])[C:9]1[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=1[C:11]([NH2:13])=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 203383632-[Benzyl(2-hydroxyethyl)amino]benzamide

Product 1

HCID 20338242HCID 20338242, compound

Procedure

2-[Benzyl(2-hydroxyethyl)amino]benzamide (10 g) was added at 0° to 50 ml SOCl2, stirred 71/2 hours at room temperature and left overnight. The mixture was concentrated on the rotovap, ethyl acetate added and the solid filtered to give 11 g product, m.171-4°.

Workup

  1. waitleft overnight
  2. concentrationThe mixture was concentrated on the rotovap, ethyl acetate
  3. additionadded
  4. filtrationthe solid filtered

Sources & evidence

ORD record
ord-bb6450f9ed414956a3d41b5dfc4f6bdd
Source dataset
uspto-grants-1977_11
Patent number
US04060526

Reaction notes

Loading…