HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6,7-dimethoxy-4-quinazolinamine → HCID 21184007, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6,7-dimethoxy-4-quinazolinamine | HCID 90235 | — |
| Reactant | Cyclobutyl(piperazin-1-yl)methanone | HCID 16777642 | — |
| Product | HCID 21184007 | HCID 21184007 | — |
Reaction Steps
N-(Cyclobutylcarbonyl)piperazine (0.02 mole) and 2-chloro-4-amino-6,7-dimethoxyquinazoline (0.02 mole) are reacted according to the procedure of Example 1(a). When reaction is complete, the solvent is removed and the residue crystallized from methanolisopropanol to provide analytically pure 4-amino-2-[4-(cyclobutylcarbonyl)-1-piperazinyl]-6,7-dimethoxyquinazoline hydrochloride hydrate, m.p. 267°-268° C. (dec.)(corr.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04060615 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-c56152e1a6574041af9a7d0416af44a5 |
| Source note | uspto-grants-1977_11 |