HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-2-thiopseudourea sulfate → Guanidine Sulfate (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-2-thiopseudourea sulfate | HCID 75270 | — |
| Reactant | 2-(3-Chloropyrid-2-ylmethylthio)ethylamine | HCID 12951532 | — |
| Solvent | Water | HCID 962 | — |
| Product | Guanidine Sulfate (1:1) | HCID 499987 | — |
Reaction Steps
A solution of 3-chloro-2-((2-aminoethyl)thiomethyl)pyridine (22.4 g) and S-methylisothiourea sulphate (15.1 ) in water (100 ml) was heated under reflux for 3 hours. Concentration, acidification with sulphuric acid and dilution with ethanol afforded 2-[3-chloro-2-pyridyl)methylthio)ethyl]guanidine sulphate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04060621 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-d4df4b25b4334009b102f24179f94ae0 |
| Source note | uspto-grants-1977_11 |