Water → 3-(Nitro-n-butylamino)benzophenone

HRID 1439788Notes

Reaction equation

HRID 1439788 reaction equation
Cl[C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][C:3]=1[N+:16]([O-])=O.[CH2:19](N)[CH2:20][CH2:21][CH3:22].O.[N+:25](C1C=C(C=CC=1NCCCC)C(C1C=CC=CC=1)=O)([O-:27])=[O:26]>C1(C)C=CC=CC=1>[N+:25]([N:16]([CH2:19][CH2:20][CH2:21][CH3:22])[C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:2]=1)[C:6]([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)=[O:7])([O-:27])=[O:26]

Participants

6

Reactant 4

HCID 962WaterHCID 8007ButylamineHCID 417434-Chloro-3-nitrobenzophenoneHCID 6205244-n-Butylamino-3-nitrobenzophenone

Product 1

HCID 205552293-(Nitro-n-butylamino)benzophenone

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of 4-chloro-3-nitrobenzophenone (13.08 g.; 0.05 mole) and n-butylamine (10.97 g.; 0.15 mole) are refluxed and stirred for 4 hours. To the reaction mixture is added water (300 ml.) and toluene (200 ml.) and the toluene layer collected and dried over magnesium sulfate. The toluene solution is filtered and the toluene removed under vacuum to afford 11.4 g. of 3-nitro-4-n-butylaminobenzophenone.

Workup

  1. temperatureare refluxed
  2. customthe toluene layer collected
  3. dry with materialdried over magnesium sulfate
  4. filtrationThe toluene solution is filtered
  5. customthe toluene removed under vacuum
  6. customto afford 11.4 g

Sources & evidence

ORD record
ord-e97de0f6d624432391909d664805b238
Source dataset
uspto-grants-1977_11
Patent number
US04060636

Reaction notes

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