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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1439804Generated: October 30, 2026

Norprostol → Methyl 7-(5-oxo-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopent-1-en-1-yl)heptanoate

https://huagongshe.com/reaction/1439804

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNorprostolHCID 3912664—
ReactantNorprostol, (-)-HCID 10823960—
ProductMethyl 7-(5-oxo-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopent-1-en-1-yl)heptanoateHCID 13216833—

Reaction Steps

When an equivalent quantity of methyl 7-(3(RS)-hydroxy-5-oxocyclopent-1-en--yl)heptanoate is substituted for the methyl 7-(3(S)-hydroxy-5-oxocyclopent-1-en-1-yl)-heptanoate and the procedure detailed in Part A substantially repeated, there is obtained methyl 7-(3(RS)-tetrahydropyran-2-yloxy-5-oxocyclopent-1-en-1-yl)heptanoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04060691
Source datasetuspto-grants-1977_11
ORD IDord-b0e609de5ad649dbbc660dc53d305c47
Source noteuspto-grants-1977_11