HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54353892, compound → 4-[2-(4-fluorophenyl)ethyl]-4′-pentyl-1,1′-Biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54353892 | HCID 54353892 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-[2-(4-fluorophenyl)ethyl]-4′-pentyl-1,1′-Biphenyl | HCID 14766836 | — |
Reaction Steps
A solution of 9.5 g of 1-(p-fluorophenyl)-2-(4'-n-pentyl-biphenyl-4-yl)ethene [obtained by Heck coupling of 4-fluorostyrene with 4-bromo-4'-n-pentylbiphenyl] in 100 ml of tetrahydrofuran is hydrogenated in the presence of Pd/C until the take-up of H is complete. Customary work-up gives 1-(p-fluorophenyl)-2-(4'-n-pentylbiphenyl-4-yl)ethane, mp. 60°, cp. 109°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05496499 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-95c1dd4227db4af69ea40a5ab7fbfea6 |
| Source note | uspto-grants-1996_03 |