HuagongsheHuagongshe Chemistry Print Report · For research reference only
Vinyl phenoxyacetate → 6-O-benzoyl-3-O-phenoxyacetylglucal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Vinyl phenoxyacetate | HCID 10954083 | — |
| Reactant | 6-O-Benzoyl-D-glucal | HCID 14308105 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 6-O-benzoyl-3-O-phenoxyacetylglucal | HCID 14541976 | 88% |
Reaction Steps
226 mg (0.90 mmol) of 6-O-benzoylglucal are dissolved in 1 ml of dimethoxyethane and stirred with 1 ml of vinyl phenoxyacetate and 220 mg of lipase Fp at room temperature for 3 hours. Filtration and flash chromatography (silica gel; hexane and ether/hexane 1:1) result in 6-O-benzoyl-3-O-phenoxyacetylglucal in 88% yield (304.5 mg, 0.79 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05496930 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-d8f53c3ccefd406481e0b2518d0903af |
| Source note | uspto-grants-1996_03 |