L-Leucine → HCID 22859209, compound
Reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5].[C:10]([S:13][CH2:14][CH:15]([CH3:19])[C:16](Cl)=[O:17])(=[O:12])[CH3:11]>>[C:10]([S:13][CH2:14][CH:15]([CH3:19])[C:16]([NH:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5])=[O:17])(=[O:12])[CH3:11]Participants
3
Procedure
Following the procedure of Example 16, L-leucine is reacted with 3-acetylthio-2-methylpropanoyl chloride to give (±)-N-[3-(acetylthio)-2-methyl -1-oxopropyl]-L-leucine.
Sources & evidence
- ORD record
- ord-7e4a806c3b3946d1b7b6242999c7d97d
- Source dataset
- uspto-grants-1996_03
- Patent number
- US05496805
Reaction notes
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