HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 14155009, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-[(Acetylthio)methyl]-3-phenylpropionic Acid | HCID 9991796 | — |
| Reactant | Methyl 5-aminopentanoate hydrochloride | HCID 13672034 | — |
| Product | HCID 14155009 | HCID 14155009 | — |
Reaction Steps
2-Acetylthiomethyl-3-phenylpropanoic acid is reacted with oxalyl chloride and the resulting acid chloride is then reacted with 5-aminopentanoic acid, methyl ester, hydrochloride in the presence of diisopropylethylamine as more fully described in Example 5 of European Patent Application 136,883 to give (±)-5-[[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]amino]pentanoic acid, methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05496805 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-56f56361128e46cd8825a4a76dcf65fc |
| Source note | uspto-grants-1996_03 |