HRID1440160

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10928

Ethyl chloroformate

C3H5ClO2

结构：CCCC[C@@H](NC(=O)[C@@H](Cc1cn(C(=O)OC)c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1

HCID15298069

未命名化合物

PRODUCTS

生成物

结构：CCCC[C@@H](NC(=O)[C@@H](Cc1cn(C(=O)OCC)c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1

HCID131719298

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using ethyl chloroformate instead of methyl chloroformate in the same manner described in Example 1-(1) and (2).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-23719d3c22b14f1095fb8b6fcd464774
来源数据集: uspto-grants-1996_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05496928
来源说明: uspto-grants-1996_03

反应 SMILES

Cl[C:2]([O:4][CH2:5][CH3:6])=[O:3].[NH:7]([C:49]([O:51][C:52]([CH3:55])([CH3:54])[CH3:53])=[O:50])[C@H:8]([C:13]([NH:15][C@@H:16]([C:31]([NH:33][C@@H:34]([C:39]([O:41][CH2:42][C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)=[O:40])[CH2:35][CH2:36][CH2:37][CH3:38])=[O:32])[CH2:17][C:18]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[N:20](C(OC)=O)[CH:19]=1)=[O:14])[CH2:9][CH:10]([CH3:12])[CH3:11]>>[NH:7]([C:49]([O:51][C:52]([CH3:55])([CH3:53])[CH3:54])=[O:50])[C@H:8]([C:13]([NH:15][C@@H:16]([C:31]([NH:33][C@@H:34]([C:39]([O:41][CH2:42][C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)=[O:40])[CH2:35][CH2:36][CH2:37][CH3:38])=[O:32])[CH2:17][C:18]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[N:20]([C:2]([O:4][CH2:5][CH3:6])=[O:3])[CH:19]=1)=[O:14])[CH2:9][CH:10]([CH3:12])[CH3:11]