HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 1-Iodo-4-(pentylthio)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | Sodium Pyrosulfite | HCID 656671 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Reactant | 1-Bromo-4-(pentylsulfanyl)benzene | HCID 12521242 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Iodo-4-(pentylthio)benzene | HCID 18982656 | — |
Reaction Steps
The Grignard reagent from the product of Step 2.1 (15 g) was prepared using magnesium in tetrahydrofuran (60 ml). Iodine (16.2 g) was added over 10 min and the mixture was stirred for 16 hrs. Water was added and then 10% sodium metabisulphite (100 ml). The product was extracted into petroleum ether and distilled. Yield 10.5 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05498366 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-c57a66ec3d16498ea0dbb64e58dc142c |
| Source note | uspto-grants-1996_03 |