Iodine → HCID 18982717, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 2-chlorophenothiazine (1.0 g; 4.26 mmol) and potassium acetate (KOAc) (2.5 g) in boiling methanol (MeOH) (70 mL) was allowed to cool to 40° C. then treated with malononitrile (0.42 g; 1.5 eq). This solution was treated at once with a solution of I2 (2.16 g) in MeOH (25 mL) and allowed to stir at ambient temperature for 3.5 h. The dark green solid that separated was collected by filtration, washed with MeOH and dried in vacuo to give 4 (0.33 g, 26%). MS (70 eV) m/e (rel. intensity) 295 (100), 260 (26).

Provenance & Evidence