反应详情

To a suspension of pyrene carboxaldehyde (9.6 g, 42 mmol) in ethanol (50 mL) was added NaBH4 (2 g) and the mixture was stirred at room temperature for 6 hours. Water (100 mL) was added and the mixture was extracted with ether (2×50 mL). The organic layer was dried over MgSO4, and the solvent evaporated under reduced pressure to give a light-yellow solid which was recrystallized from ethyl acetate to afford prisms, m.p. 125°-126° C., yield: 8.3 g, 86%.

1. extractionthe mixture was extracted with ether (2×50 mL)
2. dry with materialThe organic layer was dried over MgSO4
3. customthe solvent evaporated under reduced pressure
4. customto give a light-yellow solid which
5. customwas recrystallized from ethyl acetate
6. customto afford prisms, m.p. 125°-126° C., yield: 8.3 g, 86%