Chloroethane → HCID 18983517, compound

Participants

Reaction Conditions

Reaction Steps

96.4 g (0.528 mol) of 2,4,6-trimethylbenzoyl chloride and 1.2 g of triethylamine were heated to 115° C. and 65 g (0.264 mol) of monoethyl monophenyl phenylphosphonite were added dropwise in 75 minutes under a nitrogen atmosphere and with vigorous stirring. Ethyl chloride was given off as gas and was condensed in a downstream cold trap. The mixture was then further stirred for 2 hours at 115° C. and simultaneously a relatively strong nitrogen stream was passed through the apparatus. In total, at the end of the reaction 16 g (94% of theory) of ethyl chloride were situated in the cold trap. The excess 2,4,6-trimethylbenzoylchloride was then distilled off at 1 mbar and the residue was distilled with the aid of a thin-film evaporator (bath temperature: 230° C.; 0.3 mbar). 78 g were obtained. The yield was 81% of theory.

Provenance & Evidence