反应详情

温度

110 °C

113 g (0.496 mol) of diethyl 4-methoxyphenylphosphonite and 46.6 g (0.496 mol) of phenol were mixed and heated with stirring to 110° C. at 350-400 mbar. Ethanol distilled off during this via a small column. The temperature was then increased stepwise to 150° C., and the vacuum was simultaneously increased to 100 mbar. After completion of the reaction, the batch was cooled and distilled. 105 g were obtained having a boiling point of 159° C. at 0.4 mbar. The yield was thus 77% of theory.

1. temperatureheated
2. distillationEthanol distilled off during this via a small column
3. temperatureThe temperature was then increased stepwise to 150° C.
4. temperaturethe vacuum was simultaneously increased to 100 mbar
5. customAfter completion of the reaction
6. temperaturethe batch was cooled
7. distillationdistilled
8. custom105 g were obtained