Octadecyl isocyanate → HCID 19594339, compound

Participants

Reaction Conditions

Reaction Steps

Into a 200-ml flask equipped with a stirrer and a condenser were charged 10.0 g of 2-(p-hydroxyphenylthio)ethylamine and 120 ml of methyl ethyl ketone, and stirred with heating at 60° C. in a nitrogen stream. Into the resulting solution was slowly dropped 15.3 g of n-octadecyl isocyanate, upon which white crystals were immediately precipiated. The reaction temperature was raised to 90° C. and stirring was continued with heating for 1 hour. The reaction mixture was cooled to room temperature, after which the crystals precipitated were collected by filtration. Recrystallization from chloroform gave 27.5 g of the desired compound. Melting point: 121° C.

Provenance & Evidence