Ethylamine → HCID 18630246, compound

HRID 1440556Notes

Reaction equation

HRID 1440556 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:11]=[CH:10][CH:9]=[CH:8][C:4]=1[C:5](Cl)=[O:6].[CH2:14]([NH2:16])[CH3:15]>>[CH2:14]([NH:16][C:5](=[O:6])[C:4]1[CH:8]=[CH:9][CH:10]=[CH:11][C:3]=1[C:2]([F:13])([F:12])[F:1])[CH3:15]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 675612-(Trifluoromethyl)benzoyl chloride

Product 1

HCID 18630246HCID 18630246, compoundYield 67%

Procedure

2-(Trifluoromethyl)benzoyl chloride and ethyl amine were combined according to General Method E1 and recrystallized from cold hexanes to give 7.7 g N-ethyl-2-(trifluoromethyl)benzamide as a white solid, a 67% yield. m.p. 73°-76° C.

Workup

  1. customrecrystallized from cold hexanes

Sources & evidence

ORD record
ord-de6e5a0dcf2d4199a1c81301ad1a6e89
Source dataset
uspto-grants-1996_03
Patent number
US05498630

Reaction notes

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