Isopropylamine → HCID 18630101, compound

HRID 1440569Notes

Reaction equation

HRID 1440569 reaction equation
[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([Si:13]([CH3:16])([CH3:15])[CH3:14])[C:3]=1[C:4]([N:6]=[C:7]=[O:8])=[O:5].[CH:17]([NH2:20])([CH3:19])[CH3:18]>C1(C)C=CC=CC=1.CCCCCC.C(=O)=O>[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([Si:13]([CH3:16])([CH3:15])[CH3:14])[C:3]=1[C:4]([NH:6][C:7]([NH:20][CH:17]([CH3:19])[CH3:18])=[O:8])=[O:5]

Participants

6

Reactant 2

HCID 6363IsopropylamineHCID 18630361HCID 18630361, compound

Product 1

HCID 18630101HCID 18630101, compound

Reagents, catalysts & solvents 3

HCID 280Carbon DioxideSolventHCID 1140TolueneSolventHCID 8058HexaneSolvent

Procedure

2-Chloro-6-trimethylsilylbenzoyl isocyanate (1.3 g, 5 mmol) was dissolved in 40 mL toluene and isopropyl amine (1 g) added over a period of 30 seconds. After stirring 30 min, the solvent was removed to yield an oil. The oil was dissolved in hexane and cooled in dry ice to yield 1.2 g of crystals of the title compound. m.p. 113°-116° C.

Workup

  1. customthe solvent was removed
  2. customto yield an oil

Sources & evidence

ORD record
ord-2b7e164c183e44d0ba32e0fa6e10c322
Source dataset
uspto-grants-1996_03
Patent number
US05498630

Reaction notes

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