Ethylamine → HCID 18630087, compound

HRID 1440618Notes

Reaction equation

HRID 1440618 reaction equation
[Br:1][C:2]1[S:6][CH:5]=[C:4]([C:7]([OH:9])=O)[CH:3]=1.[CH2:10]([NH2:12])[CH3:11]>O>[Br:1][C:2]1[S:6][CH:5]=[C:4]([C:7]([NH:12][CH2:10][CH3:11])=[O:9])[CH:3]=1

Participants

4

Reactant 2

HCID 6341EthylamineHCID 120399785-Bromothiophene-3-carboxylic acid

Product 1

HCID 18630087HCID 18630087, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5-Bromo-N-ethyl-3-thiophenecarboxamide was prepared from 5-bromo-3-thiophenecarboxylic acid (2.1 g, 10 mmol) and 70% ethylamine in water according to the methods of steps a and b of Example 248 in 70% yield.

Sources & evidence

ORD record
ord-05e3665d0b8d4010a51d0c6b29f27bc3
Source dataset
uspto-grants-1996_03
Patent number
US05498630

Reaction notes

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