HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 1,8-Diazabicyclo(5.4.0)undec-7-ene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Carbamate | HCID 276 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
Reaction Steps
Namely, the substituted iminosulfonamide derivative (7) is reacted with the carbamate derivative (8) in a solvent such as acetone, acetonitrile or dioxane in the presence of an inorganic base such as potassium carbonate or an organic base such as triethylamine or 1,8-diazabicyclo[5.4.0]-7-undecene (DBU) to obtain the compound of the present invention (1:X=O).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05500406 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-c486bb95ac3649de96c007b12252c556 |
| Source note | uspto-grants-1996_03 |